Utilizing Nanobodies to Deliver Molecules to the Brain
- gphscholars
- Jul 23
- 1 min read
Presenter: Anjika Singh, Biological Sciences & Computer Science, Global Public Health Scholars
For my practicum project, I worked in the Liang Lab at the University of Maryland, School of Medicine in Baltimore. I worked as a research assistant under principal investigator Dr. Yajie (Kevin) Liang, along with other students and careers workers. I learned the basic lab techniques that were required for the lab, such as DNA/plasmid extraction, cell culturing, transformation, etc. I then worked to transfect plasmids into HEK293 cells for the purpose of tracking and multicolor labeling. I also worked on a nanobody project where our group used TFR to transport macromolecules across the blood-brain barrier to create drugs in order to treat central nervous system diseases. Some of my learning highlights included learning new techniques, collaboration, and looking into the life of a researcher. I attended lab meetings and presented my research at them, making me get the true experience of the lab. I also presented my research at the end along with other interns. My project and the other interns' research expanded my knowledge of global health by exposing me to problems that are prevalent and being solved in research currently. My practicum helped me better understand population health and the interdisciplinary approaches to public health implementation by exposing me to the problems that are prevalent. I was able to learn more about the solutions that researchers are working on to overcome the blood brain barrier. As mentioned before, the Liang lab was able to collaborate with the School of Pharmacy, allowing me to realize there are many steps when it comes to public health research.
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